Address:D404 No.69 Jinye Road, Xi'an High Tech Zone, Xi'an 710077, Shaanxi, China
English Name: Usnea Extract Powder
Botanical Source: Usnea Dasypoga Ach
Appearance: Bright Yellow Powder
Part of Plant Used: Lichen
Main Components: Usnic Acid
Specification: 98% Usnic Acid
CAS Number: 125-46-2
Method of Testing: HPLC
Expiration Date: 2 Years
Usnea Extract Powder
Usnea Dasypoga Ach
Part of Plant Used
Bright Yellow Powder
98% Usnic Acid
Total Plate Count
Yeast & Moulds
Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
Country of origin
1. Antibacterial effect
Many lichens, such as the genera, contain antibacterial substances, especially the antibacterial effects of the acid.Its antimicrobial spectrum is mainly gram-positive bacteria and tuberculous bacteria.Usnic acid in test tubes for pneumococcal, hemolytic streptococcus, corynebacterium diphtheriae, n/med tuberculosis bacili have very strong bacteriostatic action, bacteriostasis concentration of 1-5 mu g, ml, to 50 mu g/ml can completely inhibit the growth of bacteria.The inhibition of staphylococcus aureus was slightly weaker than that of above bacteria, but stronger than that of gram-negative bacteria.There was no significant difference in the antibacterial effect between right - and left - handed versions.However, there are also reports that gram-negative pertussis, subtilis, pneumococcal and even escherichia coli, proteus, dysentery and typhoid are not effective.In the in vitro experiment, the truffle acid had a significant inhibitory effect on the human tuberculous bacillus. 20-50 pleigs /ml could be completely inhibited, and the serum could slightly reduce its efficacy.Oral or intraperitoneal injection is generally considered to be effective in limiting the development of tuberculosis in vivo trials (treatment of experimental tuberculosis in guinea pigs).It was also reported that rosolic acid alone had no effect on guinea pig experimental tuberculosis, but could enhance the effect of streptomycin.In vitro, it also has mild synergistic effects with streptomycin or isoniazid.Of human lung, intestinal tuberculosis, daily oral 0.1 1.0 g sodium usnic acid salt or Evosin (including usnic acid and condensation type oak moss acid preparation) 0.1 0.5 g, some of the symptoms of TB such as cough, loss of appetite, fever or diarrhea, intestinal tuberculosis sex, get better, and even make the microscopy of n/med tuberculosis bacterium overcast, but the watch is still not perfect, not the final conclusion.The improvement of above symptom, it is not the direct effect that medicaments appears to tuberculosis bacterium, because after taking orally, the level that does not reach in the blood bacteriostatic concentration.Some people think that it has no obvious effect on human tuberculosis.Domestic treatment of tuberculosis with turmeric acid has been observed to have a certain effect.There have been many studies on the bacteriostatic mechanism of turmeric acid, some people think that it can inhibit protein synthesis, and some think that it is related to the repulsion of oxidative phosphorylation.
2. Effects on bacterial toxins and bacteriophages
Mixed with tetanus toxin or diphtheria toxin or injected within 10 minutes after the injection, mice were able to tolerate twice the lethal dose of the toxin.Two hours after the inoculation of diphtheria diphtheria in guinea pigs, 2mg/kg of turmeric acid was injected under the skin, or both of them were mixed and inoculated in guinea pigs in advance, all of which had obvious protective effects.Experimental tetanus tetanus infection in mice, the effect of combined application of bromic acid and penicillin was the best.The paper plate method proved that 0.5-5mg/ml of d-bromoic acid had anti-phage effect.
3. Effects on other pathogens
Turmeric acid also inhibits protozoa and vaginal trichomonas.Oral sodium laurate 100-150mg/kg can harm and kill the schistosoma japonicum and the hepatic schistosoma japonicum in sheep, and muscle injection can achieve better results.For the rabbit schistosomiasis, due to its high toxicity, the use of its derivative, aniline bromide, oral 200mg/kg/ day, 9 days of continuous use, also achieved good results.
4. Other functions
In rats with partial hepatectomy, the administration of rosolic acid has the effect of promoting liver regeneration.It can reduce the use of glucose and its glycogen content in isolated rat diaphragm.Anesthetized cat intravenous injection of sodium laurate 30mg/kg can increase blood glucose.D-bromoic acid can significantly inhibit the division and phosphorus uptake of fertilized eggs of starfish (ar-bacia), but has little effect on oxygen consumption.It can also inhibit the activity of new tetrazole reductase in the granule line of gastric hydroma cells (AH13AH7974) in rats.D-pinealic acid inhibits isolated guinea pigs and frog hearts.It can dilate the blood vessels in the ear of rabbit and the lower limbs of toad.It has papaverine-like effect on the isolated rabbit intestine, paralyzes the intestinal tube and antagonizes the spasm caused by barium chloride and acetylcholine.It can also relax the uterus, bronchi and intestines of rabbits and cattle.Cat intravenous anesthesia 10 mg/kg sodium usnic acid, can quickly and significantly enhance its breath, a long time to the improvement of ventilation, increase the oxygen consumption, higher temperature, the hypermetabolism, have similar DNT effect, and the toxicity is greater than the DNT.
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